Uptown New Orleans · Since 1918

The po-boy, the way
it's always been.

A little yellow house on the corner of Annunciation Street. Fried shrimp, oysters, roast beef and hot sausage on Leidenheimer bread — made by the same family for four generations.

The little yellow Domilise's house on Annunciation Street
What's good today

Come hungry.

Fried Shrimp, dressed

The house classic — the one the line is for. Get it dressed and don't overthink it.

Roast Beef with debris

Slow-cooked, gravy-soaked, gloriously messy. Bring napkins. Or don't.

The board changes when the kitchen says so. That's how it's always worked.

Dorothy 'Miss Dot' Domilise
A note from the counter
"My name is Dorothy Domilise. I make sandwiches."

— Miss Dot, who ran this counter for more than seventy years

Domilise's opened around 1918 as a neighborhood bar. A few years later the kitchen started feeding the longshoremen coming off the river, and it never really stopped. Today Miss Dot's family keeps it going — same bread, same recipes, same little yellow house on the corner.

— the Domilise family

Come see us

The little yellow house.

Domilise's Po-Boy & Bar
5240 Annunciation Street, New Orleans, LA 70115
Mon–Wed 11–3
Thu 11–5
Fri–Sat 11–7
Sun closed
© 2026 Domilise's Po-Boy & Bar. Since 1918.
Site by noli · noli.website